Pathological Hallmarks of Alzheimer’s Disease

The neuropathological signs of Alzheimer sickness (AD) incorporate "positive" injuries, for example, amyloid plaques and cerebral amyloid angiopathy, neurofibrillary tangles, and glial reactions, and "negative" sores, for example, neuronal and synaptic misfortune. In spite of their characteristically cross-sectional nature, posthumous examinations have empowered the organizing of the movement of both amyloid and tangle pathologies, and, thus, the improvement of analytic criteria that are currently utilized around the world.

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